Undenatured Collagen Type II (UC-II style)
Non-hydrolyzed (undenatured) Type II collagen sourced from chicken sternal cartilage and processed under low-temperature conditions to preserve the native triple-helix structure. Mechanism of action is different from hydrolyzed collagen: undenatured Type II is dosed at very low levels (typically 10–40 mg/day) and acts via oral tolerance at Peyer's patches in the gut, modulating the immune response to joint cartilage.
CAS Number
9007-34-5
Physical Form
Fine pale-yellow to off-white powder
Typical Assay
Standardized to native (undenatured) Type II collagen content by ELISA
Origins
Chicken sternal cartilage
Purpose and Key Benefits
Joint comfort and mobility at low-dose (~40 mg). Strong clinical backing for osteoarthritis and exercise-induced joint discomfort. Allows small, low-cost capsule formats vs. multi-gram glucosamine/chondroitin stacks.
Applications
Low-dose joint capsules, premium joint-comfort stacks, sports-recovery supplements, companion-animal joint products
Certifications
NSF-GMP Registered
NSF/ANSI 173 Section 8 · FSMA and 21 CFR Part 111/117 compliant.
NSF/ANSI 173 Sec 8
ISO 9001:2015
Quality management system.
:2015 — valid to Oct 11, 2027
ISO 22000:2018
Food safety management system.
:2018 Food Safety — valid to Oct 11, 2027
ISO 14001:2015
Environmental management system.
:2015 Environmental — valid to Nov 4, 2027
ISO 45001:2018
Occupational health and safety management system.
:2018 OH&S — valid to Nov 4, 2027
FAMI-QS Certified
Specialty feed-ingredient GMP Category K.
feed-chain certification Cat K, Registration FAM-1963; renewal in process